At Esteem Clinic, we provide evidence-based treatments to support skin health. REJURAN® uses polynucleotides from salmon DNA to encourage natural skin repair and improve texture and elasticity.
Disclaimer: This information is intended for educational purposes only. It is not promotional and does not recommend or encourage any treatment.
Esteem Clinic is proud to have been awarded “Best Aesthetic Practice” by the prestigious My Face My Body Awards, for three consecutive years in a row.
At Esteem Clinic, we provide evidence-based treatments and cosmetic procedures aimed at supporting skin health and repair. Our team focuses on safe, effective, and tailored care for each patient.
The Polynucleotide therapy, also known as REJURAN®, is an injectable skin treatment that delivers polynucleotides (PDRN treatments) derived from salmon DNA. These molecules work at a cellular level to support natural skin repair and tissue regeneration, helping to improve skin texture, skin elasticity, and hydration.
Each treatment begins with a complimentary consultation, where our practitioners assess your skin and develop a personalised plan based on your individual needs.
REJURAN® works by delivering polynucleotides (PDRN) directly into the skin through controlled microinjections. These polynucleotides are biocompatible molecules that may support:
The treatment involves multiple small injections just beneath the skin surface, creating temporary visible ‘blebs’ or small raised areas. This injectable treatment is administered by qualified healthcare professionals following a comprehensive assessment and treatment planning.
Polynucleotide therapy can be applied to various areas of the face and body to address different skin concerns:
* Each treatment area requires individual assessment to determine suitability and expected outcomes
Every REJURAN® treatment at Esteem Clinic begins with a comprehensive complimentary consultation. During this appointment, our practitioners will:
A qualified healthcare professional makes the final decision on whether the treatment is appropriate, based on your individual clinical assessment.
During the session:
Regular follow-up sessions may be suggested to maintain results. The timing and frequency of these sessions will be personalised based on your response to treatment and your skin goals.
Our team brings decades of combined experience in aesthetic medicine and cosmetic treatments. Each practitioner is trained in the latest techniques and maintains strict adherence to clinical safety standards. We focus on using high-quality, clinically tested products and applying them in a way that is safe, effective, and tailored to each patient. This experience allows us to manage a wide range of skin concerns with confidence and precision.
REJURAN® is the clinical name for the Polynucleotide therapy, an injectable skin treatment that uses polynucleotides (PDRN) derived from salmon DNA. It supports the skin’s natural repair processes, promoting collagen, elastin and hyaluronic acid production, tissue regeneration, and overall improvement in skin quality.
Salmon sperm, in the form used in a facial, contains polynucleotides that help support cellular repair in the skin. Clinical studies suggest it can improve skin texture, elasticity, hydration, and overall skin health when administered as part of a controlled, injectable treatment.
The polynucleotides in salmon sperm extract work at a cellular level to support the skin’s natural repair mechanisms. They help stimulate collagen and elastin production, improve hydration, and encourage tissue regeneration, which can enhance skin texture and firmness over time.
The cost of a REJURAN® facial varies depending on:
For detailed pricing and package options, we recommend a consultation with our experienced team. During this appointment, we will review your skin goals, assess suitability, and provide a tailored plan with a clear outline of costs.
REJURAN® facial treatments use polynucleotides derived from salmon DNA. Individuals with salmon or seafood allergies should not have this treatment. Safety is assessed during your consultation to ensure it is appropriate for you.
Results vary between individuals. Some patients notice improvements after the first treatment, while others see gradual changes over several months as the skin’s natural repair processes are supported. Factors such as genetics, lifestyle, and existing skin condition can influence results.
The number of sessions depends on your individual skin concerns, goals, and response to treatment. Most patients benefit from a series of treatments spaced several weeks apart. Your practitioner will recommend a personalised plan during your consultation.
Common temporary effects include:
These effects typically resolve within 24–48 hours. Your practitioner will provide specific aftercare instructions to support recovery.
Combination treatments may be suitable depending on your skin condition and goals. Your practitioner will assess your suitability for any additional procedures during your consultation.
A REJURAN® facial uses polynucleotides (PDRN) derived from salmon DNA to support natural cellular repair and tissue regeneration. This differs from other treatments that work through alternative mechanisms. Your practitioner can explain how polynucleotide therapy compares to other options during your consultation.
The REJURAN® is generally well-tolerated, but it may not be suitable for everyone. Contraindications include:
A thorough consultation and medical assessment are essential to determine suitability and minimise risks.
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Saturday: 9 am–5 pm
Sunday: Closed
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